JAK3-IN-1
Cat. No.：YN340217
CAS No. ：1805787-93-2
规格
价格(RMB)
库存
| 产品名称: | JAK3-IN-1 |
| CAS No.: | 1805787-93-2 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 508.02 |
| 分子式: | C₂₆H₃₀ClN₇O₂ |
| SMILES: | O=C(C=C)NC1=CC(CNC2=NC(NC3=C(OC)C=C(N4CCN(C)CC4)C=C3)=NC=C2Cl)=CC=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | JAK3-IN-1 是一种有效，选择性和口服活性的JAK3抑制剂，IC50为 4.8 nM。与 JAK1 (IC50为 896 nM) 和 JAK 2 (IC50为 1050 nM) 相比，JAK3-IN-1 对JAK3的选择性高 180 倍以上。 |
| IC50和靶点: | [{name:"JAK3:4.8 nM (IC50)"},{name: "JAK1:896 nM (IC50)"},{name: "JAK2:1050 nM (IC50)"},{name: "TTK:49 nM (IC50)"},{name: "BTK:794 nM (IC50)"},{name: "ITK:1070 nM (IC50)"}] |
| In Vitro: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
