NSC 33994
Cat. No.：YN340207
| 产品名称: | NSC 33994 |
| CAS No.: | 82058-16-0 |
| Chemical Name: | 4,4'-[(1E)-1,2-Diethyl-1,2-ethenediyl]bis[2-[(diethylamino)methyl]phenol; (E)-4,4'-(1,2-Diethyl-1,2-ethenediyl)bis[2-[(diethylamino)methyl]phenol; |
| Synonyms: | |
| 分子量: | 438.65 |
| 分子式: | C₂₈H₄₂N₂O₂ |
| SMILES: | CC/C(C1=CC=C(O)C(CN(CC)CC)=C1)=C(C2=CC=C(O)C(CN(CC)CC)=C2)/CC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | NSC 33994 (G6) 是选择性的JAK2抑制剂，其 IC50值为 60 nM。 |
| IC50和靶点: | [{name:"JAK2:60 nM (IC50, JAK2 Val617Phe kinase activity )"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Tanner, J., et al.: J. Biol. Chem., 270, 6523 (1995), Rane, S., et al.: Oncogene, 19, 5662 (2000, Verma, A., et al.: Cancer Metastasis Rev., 22, 423 (2003), Levine, R., et al.: Cancer Cell., 7, 387 (2005), Kiss, et al.: Bioorg. Med. Chem. Lett., 19, 3598 (2009),
