Adavivint
Cat. No.：YN450030
CAS No. ：1467093-03-3
规格
价格(RMB)
库存
| 产品名称: | Adavivint |
| CAS No.: | 1467093-03-3 |
| Chemical Name: | Lorecivivint; N-[5-[3-[7-(3-Fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-5-yl]-3-pyridinyl]-3-methylbutanamide; N-(5-(3-(7-(3-Fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl)-1H-indazol-5-yl)pyridin-3-yl)-3-methylbutanamide; SM 04690; |
| Synonyms: | SM04690; Lorecivivint |
| 分子量: | 505.55 |
| 分子式: | C₂₉H₂₄FN₇O |
| SMILES: | CC(C)CC(NC1=CC(C2=CC3=C(NN=C3C(N4)=NC5=C4C(C6=CC=CC(F)=C6)=CN=C5)C=C2)=CN=C1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Adavivint (SM04690; Lorecivivint) 是一种有效的，选择性的典型的Wnt信号通路抑制剂，在 SW480 细胞中，用高通量 TCF/LEF 报告基因实验，测得EC50值为 19.5 nM。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Sabha, M., et al.: Expert Opin.Invest. Drugs, 29, 1339 (2020)
Sabha, M., et al.: Expert Opin.Invest. Drugs, 29, 1339 (2020)
