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Wogonin

Cat. No.:YN450142

  • CAS No. :632-85-9

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    • 产品名称: Wogonin
      CAS No.: 632-85-9
      Chemical Name: 5,7-dihydroxy-8-methoxy-2-phenyl-4H-1-benzopyran-4-one
      Synonyms:汉黄芩素
      分子量:284.26
      分子式:C₁₆H₁₂O₅
      SMILES:O=C1C=C(C2=CC=CC=C2)OC3=C(OC)C(O)=CC(O)=C13
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Wogonin 是一种天然黄酮类物质,能够抑制CDK8和Wnt的活性,具有抗炎、抗肿瘤等功效。
      IC50和靶点:
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    • Huang, W.H., Chien, P.Y., Yang, C.H., et al.Novel synthesis of flavonoids of Scutellaria baicalensis GEORGIChem. Pharm. Bull. (Tokyo)51(3),339-340(2003)

      Lee, H., Kim, Y.O., Kim, H., et al.Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microgliaFASEB J.17(13),1943-1944(2003)

      Lin, C.C., Kuo, C.L., Lee, M.H., et al.Wogonin triggers apoptosis in human osteosarcoma U-2 OS cells through the endoplasmic reticulum stress, mitochondrial dysfunction and caspase-3-dependent signaling pathwaysInt. J. Oncol.39(1),217-224(2011)

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