IWR-1
Cat. No.：YN450051
CAS No. ：1127442-82-3
规格
价格(RMB)
库存
| 产品名称: | IWR-1 |
| CAS No.: | 1127442-82-3 |
| Chemical Name: | 4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinyl-benzamide |
| Synonyms: | endo-IWR 1; |
| 分子量: | 409.44 |
| 分子式: | C₂₅H₁₉N₃O₃ |
| SMILES: | O=C(NC1=C2N=CC=CC2=CC=C1)C3=CC=C(N(C([C@]4([H])[C@](C5)([H])C=C[C@]5([H])[C@]64[H])=O)C6=O)C=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | IWR-1是端锚聚合酶抑制剂，抑制Wnt/β-catenin信号传导途径。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
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Chen, B., Dodge, M.E., Tang, W., et al.Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancerNat. Chem. Biol.5(2),100-107(2009)
Lu, J., Ma, Z., Hsieh, J.C., et al.Structure-activity relationship studies of small-molecule inhibitors of Wnt responseBioorg. Med. Chem. Lett.19(14),3825-3827(2009)
