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10-Oxo Docetaxel

Cat. No.:YN290400

  • CAS No. :167074-97-7

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    • 参考文献
    • 产品名称: 10-Oxo Docetaxel
      CAS No.: 167074-97-7
      Chemical Name: (αR,βS)-β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-benzenepropanoic acid, (2aR,4S,4aS,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5,6-dioxo-7,11-methano-1H
      Synonyms:Docetaxel Impurity 1
      分子量:805.86
      分子式:C₄₃H₅₁NO₁₄
      SMILES:CC(O[C@@]1([C@](C[C@@H]2O)([H])OC1)[C@@]([C@@]2(C3=O)C)([H])[C@@H]([C@@](C4(C)C)(C[C@H](OC([C@H](O)[C@H](C5=CC=CC=C5)NC(OC(C)(C)C)=O)=O)C(C)=C4C3=O)O)OC(C6=CC=CC=C6)=O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: 10-Oxo Docetaxel (Docetaxel Impurity 1) 是新型紫杉烷,具有明显的抗肿瘤活性,是多西他赛(docetaxel)的中间体。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Malleswara Reddy, A., Banda, N., Govind Dagdu, S., et al.Evaluation of the pharmaceutical quality of docetaxel injection using new stability indicating chromatographic methods for assay and impuritiesSci. Pharm.78(2),215-231(2010)

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