Docetaxal
Cat. No.：YN290497
| 产品名称: | Docetaxal |
| CAS No.: | 125354-16-7 |
| Chemical Name: | (αR,βS)-β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-benzenepropanoic acid, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methan |
| Synonyms: | 10-Acetyl docetaxel; PNU-101383 |
| 分子量: | 849.92 |
| 分子式: | C₄₅H₅₅NO₁₅ |
| SMILES: | CC(O[C@@]1([C@](C2)([H])OC1)[C@@]([C@](C([C@@H]3OC(C)=O)=O)([C@H]2O)C)([H])[C@@H]([C@@](C(C)(C3=C4C)C)(C[C@@H]4OC([C@H](O)[C@H](C5=CC=CC=C5)NC(OC(C)(C)C)=O)=O)O)OC(C6=CC=CC=C6)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Docetaxal (10-Acetyl docetaxel; PNU-101383) 是一种 Docetaxel (HY-B0011) 类似物。Docetaxal 是一微管拆卸microtubule disassembly抑制剂，具有抗有丝分裂活性。Docetaxal 对小鼠白血病细胞具有细胞毒性。 |
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Swindell, C.S., Heerding, J.M., Krauss, N.E., et al.Characterization of the taxol structure-activity profile for the locus of the A-ring side chainBioorg. Med. Chem. Lett.4(12),1531-1536(1994)
