SR-3677
Cat. No.：YN450076
CAS No. ：1072959-67-1
规格
价格(RMB)
库存
| 产品名称: | SR-3677 |
| CAS No.: | 1072959-67-1 |
| Chemical Name: | N-[2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxin-2-carboxamide |
| Synonyms: | SR-3677; SR 3677 |
| 分子量: | 408.45 |
| 分子式: | C₂₂H₂₄N₄O₄ |
| SMILES: | CN(C)CCOC1=C(NC(C2OC(C=CC=C3)=C3OC2)=O)C=CC(C4=CNN=C4)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SR-3677是高效的选择性的ROCK-II抑制剂，IC50值为~3 nM。 |
| IC50和靶点: | [{name:"ROCK-II:3 nM (IC50)"},{name: "ROCK-I:56 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Feng, Y., Yin, Y., Weiser, A., et al.Discovery of substituted 4-(pyrazol-4-yl)-phenylbenzodioxane-2-carboxamides as potent and highly selective Rho kinase (ROCK-II) inhibitorsJ. Med. Chem.51(21),6642-6645(2008)
