Verosudil
Cat. No.：YN450121
CAS No. ：1414854-42-4
规格
价格(RMB)
库存
| 产品名称: | Verosudil |
| CAS No.: | 1414854-42-4 |
| Chemical Name: | |
| Synonyms: | AR-12286 |
| 分子量: | 327.40 |
| 分子式: | C₁₇H₁₇N₃O₂S |
| SMILES: | O=C(NC1=CC2=C(C(NC=C2)=O)C=C1)C(N(C)C)C3=CSC=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Verosudil (AR-12286) 是一种有效的 Rho 激酶(ROCK)抑制剂，对 ROCK1 和 ROCK2 的Ki分别为 2 和 2 nM。AR-12286 主要通过增加眼房水通过小梁网流出来降低眼压。 |
| IC50和靶点: | [{name:"ROCK1:2 nM (Ki)"},{name: "ROCK2:2 nM (Ki)"},{name: "PKA:69 nM (Ki)"},{name: "MRCKA:28 nM (Ki)"},{name: "CAM2A:5855 nM (Ki)"},{name: "PKC theta:9322 nM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
