Ripasudil free base
Cat. No.：YN450106
CAS No. ：223645-67-8
规格
价格(RMB)
库存
| 产品名称: | Ripasudil free base |
| CAS No.: | 223645-67-8 |
| Chemical Name: | |
| Synonyms: | K-115 (free base) |
| 分子量: | 323.39 |
| 分子式: | C₁₅H₁₈FN₃O₂S |
| SMILES: | FC1=CN=CC2=C1C(S(N3CCCNC[C@@H]3C)(=O)=O)=CC=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ripasudil free base (K-115 free base) 是ROCK特异性抑制剂，能够抑制ROCK2和ROCK1的活性，IC50值分别为 19 和 51 nM。 |
| IC50和靶点: | [{name:"ROCK2:19 nM (IC50)"},{name: "ROCK1:51 nM (IC50)"},{name: "CaMKIIa:370 nM (IC50)"},{name: "PKACa:2.1 μM (IC50)"},{name: "PKC:27 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
