Roemerine
Cat. No.：YN360318
| 产品名称: | Roemerine |
| CAS No.: | 548-08-3 |
| Chemical Name: | 6,7aR,7a,8-tetrahydro-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline |
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| 分子量: | 279.33 |
| 分子式: | C₁₈H₁₇NO₂ |
| SMILES: | CN1CCC(C2=C3C4=CC=CC=C4C[C@@]12[H])=CC5=C3OCO5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Roemerine 是可从Annona senegalensis叶子中分离得到的一种生物碱、通过P-glycoprotein发挥作用。Roemerine 可逆转培养细胞的多药耐药表型。 |
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Agnihotri, V.K., ElSohly, H.N., Khan, S.I., et al.Constituents of Nelumbo nucifera leaves and their antimalarial and antifungal activityPhytochem. Lett.1(2),89-93(2008)
Munusamy, V., B.K., Y., Buckle, M.J.C., et al.Structure-based identification of aporphines with selective 5-HT2A receptor-binding activityChem. Biol. Drug Des.81(2),250-256(2012)
You, M., Wickramaratne, D.B.M., Silva, G.L., et al.(﹘)-Roemerine, an aporphine alkaloid from Annona senegalensis that reverses the multidrug-resistance phenotype with cultured cellsJ. Nat. Prod.58(4),598-604(1995)
Yin, S., Rao, G., Wang, J., et al.Roemerine improves the survival rate of septicemic BALB/c mice by increasing the cell membrane permeability of Staphylococcus aureusPLoS One10(11),e0143863(2015)
