Roquefortine C
Cat. No.：YN361002
| 产品名称: | Roquefortine C |
| CAS No.: | 58735-64-1 |
| Chemical Name: | (3E,5aS,10bR)-10b-(1,1-dimethyl-2-propen-1-yl)-6,10b,11,11aS-tetrahydro-3-(1H-imidazol-5-ylmethylene)-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione |
| Synonyms: | 异烟棒曲霉素 C |
| 分子量: | 389.45 |
| 分子式: | C₂₂H₂₃N₅O₂ |
| SMILES: | O=C([C@](N1C/2=O)([H])C[C@]3(C(C)(C)C=C)[C@@]1([H])NC4=C3C=CC=C4)NC2=C\C5=CN=CN5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Roquefortine C 是一种从罗氏青霉分离的真菌环肽，可激活P-gp并抑制P450-3A和其他血红蛋白。Roquefortine C 对革兰氏阳性细菌具有抑菌活性。 |
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García-Rico, R.O., Chávez, R., Fierro, F., et al.Effect of a heterotrimeric G protein α subunit on conidia germination, stress response, and roquefortine C production in Penicillium roquefortiInt. Microbiol.12(2),123-129(2009)
Richard, D.J., Schiavi, B., and Joullié, M.M.Synthetic studies of roquefortine C: Synthesis of isoroquefortine C and a heterocycleProc. Natl. Acad. Sci. USA101(33),11971-11976(2004)
Aninat, C., André, F., and Delaforge, M.Oxidative metabolism by P450 and function coupling to efflux systems: Modulation of mycotoxin toxicityFood Addit. Contam.22(4),361-368(2005)
Tiwary, A.K., Puschner, B., and Poppenga, R.H.Using roquefortine C as a biomarker for penitrem A intoxicationJ. Vet. Diagn. Invest.21(2),237-239(2009)
