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Isosinensetin

Cat. No.:YN360959

  • CAS No. :17290-70-9

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    • 生物活性
    • 参考文献
    • 产品名称: Isosinensetin
      CAS No.: 17290-70-9
      Chemical Name: 2-(3,4-dimethoxyphenyl)-5,7,8-trimethoxy-4H-1-benzopyran-4-one
      Synonyms:异橙黄酮
      分子量:372.37
      分子式:C₂₀H₂₀O₇
      SMILES:O=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=C(OC)C(OC)=CC(OC)=C13
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Isosinensetin 是从青皮中提取的一种甲氧基黄酮类化合物, 对 MDR1-MDCKII 细胞中的 p- 糖蛋白(P-gp)具有抑制作用。
      IC50和靶点:
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      In Vivo:
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    • Bai, J., Zhao, S., Fan, X., et al.Inhibitory effects of flavonoids on P-glycoprotein in vitro and in vivo: Food/herb-drug interactions and structure-activity relationshipsToxicol. Appl. Pharmacol.369,49-59(2019)

      Du, Q., and Chen, H.The methoxyflavones in Citrus reticulata Blanco cv. ponkan and their antiproliferative activity against cancer cellsFood Chem.119(2),567-572(2010)

      Zou, Y., Li, S., Li, X., et al.Isosinensetin alleviates the injury of human bronchial epithelial cells induced by PM2.5Exp. Ther. Med.22(6),1435(2021)

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