(R)-Verapamil hydrochloride
Cat. No.：YN360433
CAS No. ：38176-02-2
| 产品名称: | (R)-Verapamil hydrochloride |
| CAS No.: | 38176-02-2 |
| Chemical Name: | (αR)-α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-benzeneacetonitrile Hydrochloride; (R)-Verapamil Hydrochloride; Dexverapamil Hydrochloride; LU 33925; NSC 632821; |
| Synonyms: | (R)-(+)-Verapamil hydrochloride |
| 分子量: | 491.06 |
| 分子式: | C₂₇H₃₉ClN₂O₄ |
| SMILES: | COC1=C(OC)C=CC(CCN(C)CCC[C@](C#N)(C2=CC(OC)=C(OC)C=C2)C(C)C)=C1.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | (R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) 是一种 P-糖蛋白 (P-Glycoprotein) 抑制剂。(R)-Verapamil hydrochloride 抑制 MRP1 介导的转运，导致 MRP1 过表达细胞对抗癌药产生化学敏感性。 |
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| Solvent & Solubility: |
Peroutka, S., et al.: J. Ann. Neurol, 23, 500 (1988)
Eliason, J.F., et al.: Int. J. Cancer, 46, 113 (1990)
