Encequidar
Cat. No.:YN360450
CAS No. :849675-66-7
产品名称: | Encequidar |
CAS No.: | 849675-66-7 |
Chemical Name: | N-[2-[2-[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-2H-tetrazol-5-yl]-4,5-dimethoxyphenyl]-4-oxo-4H-1-benzopyran-2-carboxamide |
Synonyms: | HM30181; HM30181A |
分子量: | 688.73 |
分子式: | C₃₈H₃₆N₆O₇ |
SMILES: | O=C(C1=CC(C2=CC=CC=C2O1)=O)NC3=CC(OC)=C(OC)C=C3C4=NN(C5=CC=C(CCN6CC7=C(C=C(OC)C(OC)=C7)CC6)C=C5)N=N4 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Encequidar (HM30181; HM30181A) 是一种有效的选择性的P-glycoprotein抑制剂。 |
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Kwak, J.-O., Lee, S.H., Lee, G.S., et al.Selective inhibition of MDR1 (ABCB1) by HM30181 increases oral bioavailability and therapeutic efficacy of paclitaxelEur. J. Pharmacol.627(1-3),92-98(2009)