Dofequidar
Cat. No.：YN360603
| 产品名称: | Dofequidar |
| CAS No.: | 129716-58-1 |
| Chemical Name: | 1-[4-[2-hydroxy-3-(5-quinolinyloxy)propyl]-1-piperazinyl]-2,2-diphenyl-ethanone |
| Synonyms: | MS-209; MS 209; MS209; Dofequidar |
| 分子量: | 481.59 |
| 分子式: | C₃₀H₃₁N₃O₃ |
| SMILES: | OC(COC1=C2C=CC=NC2=CC=C1)CN3CCN(C(C(C4=CC=CC=C4)C5=CC=CC=C5)=O)CC3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dofequidar(MS-209)是新型的喹啉化合物，能逆转P-糖蛋白（P-gp）介导的多药抗性。 |
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Sato, W., Fukazawa, N., Nakanishi, O., et al.Reversal of multidrug resistance by a novel quinoline derivative, MS-209Cancer Chemother. Pharmacol.35(4),271-277(1995)
Narasaki, F., Oka, M., Fukuda, M., et al.A novel quinoline derivative, MS-209, overcomes drug resistance of human lung cancer cells expressing the multidrug resistance-associated protein (MRP) geneCancer Chemother. Pharmacol.40(5),425-432(1997)
