NSC23925
Cat. No.:YN360686
产品名称: | NSC23925 |
CAS No.: | 858474-14-3 |
Chemical Name: | 2-(4-methoxyphenyl)-α-2-piperidinyl-4-quinolinemethanol, dihydrochloride |
Synonyms: | NSC23925 |
分子量: | 421.36 |
分子式: | C₂₂H₂₆Cl₂N₂O₂ |
SMILES: | OC(C1NCCCC1)C2=CC(C3=CC=C(OC)C=C3)=NC4=CC=CC=C24.[H]Cl.[H]Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | NSC23925 是一种新型的,有选择性且有效的 P-糖蛋白 (Pgp) 抑制剂。 |
IC50和靶点: | |
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Duan, Z., Choy, E., and Hornicek, F.J.NSC23925, identified in a high-throughput cell-based screen, reverses multidrug resistancePLoS One4(10),e7415(2009)
Yang, X., Feng, Y., Gao, Y., et al.NSC23925 prevents the emergence of multidrug resistance in ovarian cancer in vitro and in vivoGynecol. Oncol.137(1),134-142(2015)