Convallatoxin
Cat. No.：YN360977
| 产品名称: | Convallatoxin |
| CAS No.: | 508-75-8 |
| Chemical Name: | (3β,5β)-3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxo-Card-20(22)-enolide; Convallaotoxin; Convallaton; Convallatoxine; Convallatoxoside; Convallotoxin; Corglycon; Corglycone; Corglykon; Korglykon; NSC 407808; Strophanthidin α-L-Rhamnoside |
| Synonyms: | 铃兰毒苷 |
| 分子量: | 550.64 |
| 分子式: | C₂₉H₄₂O₁₀ |
| SMILES: | O=C1OCC([C@H]2CC[C@]3(O)[C@]4([H])CC[C@]5(O)C[C@@H](O[C@H]6[C@@H]([C@@H]([C@H]([C@H](C)O6)O)O)O)CC[C@]5(C=O)[C@@]4([H])CC[C@]23C)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Convallatoxin 是从Adonis amurensis Regel et Radde分离得到的强心苷。Convallatoxin 通过激活PPARγ和抑制NF-κB改善结肠炎。Convallatoxin 是一种 P-糖蛋白 (P-gp) 底物，并识别 Val982 是参与其转运的重要氨基酸。Convallatoxin 是配体诱导的 MOR 胞吞作用的增强剂，具有很高的效力和功效。具有抗炎和抗增殖特性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Schneider, N., et al.: Nat. Prod. Res., (2015)
Yin, L., et al.: Zhong Cao Yao, 45, 3361 (2014)
