Hypophyllanthin
Cat. No.:YN360987
产品名称: | Hypophyllanthin |
CAS No.: | 33676-00-5 |
Chemical Name: | (7S,8S,9R)-9-(3,4-dimethoxyphenyl)-6,7,8,9-tetrahydro-4-methoxy-7,8-bis(methoxymethyl)-naphtho[1,2-d]-1,3-dioxole |
Synonyms: | 叶下珠次素,(7S,8S,9R)-9-(3,4-二甲氧基苯基)-6,7,8,9-四氢-4-甲氧基-7,8-双(甲氧基甲基)萘并[1,2-D]-1,3-二恶茂 |
分子量: | 430.49 |
分子式: | C₂₄H₃₀O₇ |
SMILES: | COC[C@@H]1[C@@H](COC)CC2=CC(OC)=C(OCO3)C3=C2[C@H]1C4=CC=C(OC)C(OC)=C4 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Hypophyllanthin 是Phyllanthus spp中主要的一种木质素,具有很强的抗炎活性。Hypophyllanthin 能直接抑制P-gp的活性,而不干扰 MRP2 活性。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Murali, B., Amit, A., Anand, M.S., et al.An improved HPLC method for estimation of phyllanthin and hypophyllanthin in Phyllanthus amarusJournal of Natural Remedies1(1),55-59(2001)
Sukhaphirom, N., Vardhanabhuti, N., Chirdchupunseree, H., et al.Phyllanthin and hypophyllanthin inhibit function of P-gp but not MRP2 in Caco-2 cellsJ. Pharm. Pharmacol.65,292-299(2012)