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Hypophyllanthin

Cat. No.:YN360987

  • CAS No. :33676-00-5

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    • 生物活性
    • 参考文献
    • 产品名称: Hypophyllanthin
      CAS No.: 33676-00-5
      Chemical Name: (7S,8S,9R)-9-(3,4-dimethoxyphenyl)-6,7,8,9-tetrahydro-4-methoxy-7,8-bis(methoxymethyl)-naphtho[1,2-d]-1,3-dioxole
      Synonyms:叶下珠次素,(7S,8S,9R)-9-(3,4-二甲氧基苯基)-6,7,8,9-四氢-4-甲氧基-7,8-双(甲氧基甲基)萘并[1,2-D]-1,3-二恶茂
      分子量:430.49
      分子式:C₂₄H₃₀O₇
      SMILES:COC[C@@H]1[C@@H](COC)CC2=CC(OC)=C(OCO3)C3=C2[C@H]1C4=CC=C(OC)C(OC)=C4
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Hypophyllanthin 是Phyllanthus spp中主要的一种木质素,具有很强的抗炎活性。Hypophyllanthin 能直接抑制P-gp的活性,而不干扰 MRP2 活性。
      IC50和靶点:
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    • Murali, B., Amit, A., Anand, M.S., et al.An improved HPLC method for estimation of phyllanthin and hypophyllanthin in Phyllanthus amarusJournal of Natural Remedies1(1),55-59(2001)

      Sukhaphirom, N., Vardhanabhuti, N., Chirdchupunseree, H., et al.Phyllanthin and hypophyllanthin inhibit function of P-gp but not MRP2 in Caco-2 cellsJ. Pharm. Pharmacol.65,292-299(2012)

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