Pyr3
Cat. No.:YN360209
CAS No. :1160514-60-2
产品名称: | Pyr3 |
CAS No.: | 1160514-60-2 |
Chemical Name: | 1-[4-[(2,3,3-trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid, ethyl ester |
Synonyms: | |
分子量: | 456.63 |
分子式: | C₁₆H₁₁Cl₃F₃N₃O₃ |
SMILES: | O=C(C1=C(C(F)(F)F)N(C2=CC=C(NC(/C(Cl)=C(Cl)/Cl)=O)C=C2)N=C1)OCC |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Pyr3 是TRPC3的选择性抑制剂,其对 TRPC3 介导的 Ca2+内流的IC50值为 700 nM。 |
IC50和靶点: | |
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Solvent & Solubility: |
Kiyonaka, S., Kato, K., Nishida, M., et al.Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compoundProc. Natl. Acad. Sci. USA106(13),5400-5405(2009)