Beta-Eudesmol
Cat. No.：YN360993
| 产品名称: | Beta-Eudesmol |
| CAS No.: | 473-15-4 |
| Chemical Name: | (2R,4aR,8aS)-decahydro-α,α,4a-trimethyl-8-methylene-2-naphthalenemethanol |
| Synonyms: | β-桉叶醇 |
| 分子量: | 222.37 |
| 分子式: | C₁₅H₂₆O |
| SMILES: | C[C@]12[C@@](C(CCC2)=C)([H])C[C@H](C(C)(O)C)CC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Beta-Eudesmol 是一种天然的含氧倍半萜烯，可活化hTRPA1，EC50值为 32.5 μM。Beta-Eudesmol 可通过hTRPA1增加食欲。 |
| IC50和靶点: | |
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Kimura, M., Nojima, H., Muroi, M., et al.Mechanism of the blocking action of β-eudesmol on the nicotinic acetylcholine receptor channel in mouse skeletal musclesNeuropharmacology30(8),835-841(1991)
Ma, E.L., Li, Y.C., Tsuneki, H., et al.β-Eudesmol suppresses tumour growth through inhibition of tumour neovascularisation and tumour cell proliferationJ. Asian Nat. Prod. Res.10(1-2),159-167(2008)
Ohara, K., Fukada, T., Okada, H., et al.Identification of significant amino acids in multiple transmembrane domains of human transient receptor potential ankyrin 1 (TRPA1) for activation by eudesmol, an oxygenized sesquiterpene in hop essential oilJ. Biol. Chem.290(5),3161-3171(2015)
Ohara, K., Fukuda, T., Ishida, Y., et al.β-Eudesmol, an oxygenized sesquiterpene, stimulates appetite via TRPA1 and the autonomic nervous systemSci. Rep.7(1),15785(2017)
