Pyr10
Cat. No.：YN360679
| 产品名称: | Pyr10 |
| CAS No.: | 1315323-00-2 |
| Chemical Name: | |
| Synonyms: | Pyr-10;Pyr 10 |
| 分子量: | 449.37 |
| 分子式: | C₁₈H₁₃F₆N₃O₂S |
| SMILES: | O=S(C1=CC=C(C)C=C1)(NC2=CC=C(N3N=C(C(F)(F)F)C=C3C(F)(F)F)C=C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pyr10 是一种吡唑衍生物和一种选择性TRPC3通道抑制剂。Pyr10 抑制卡巴可刺激的TRPC3转染的 HEK293 细胞中的 Ca2+流入，IC50为 0.72 μM (对于 BRL-2H3 细胞中存储的 Ca2+进入，IC50为 13.08 μM)。Pyr10 具有区分受体操纵的TRPC3和天然基质相互作用分子 1 (STIM1)/Orai1 通道的能力。 |
| IC50和靶点: | [{name:"TRPC3:0.72 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
