Dihydrocapsaicin
Cat. No.:YN360923
CAS No. :19408-84-5
产品名称: | Dihydrocapsaicin |
CAS No.: | 19408-84-5 |
Chemical Name: | N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-nonanamide |
Synonyms: | 二氢辣椒素,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide,CCRIS1589 |
分子量: | 307.43 |
分子式: | C₁₈H₂₉NO₃ |
SMILES: | CC(C)CCCCCCC(NCC1=CC=C(O)C(OC)=C1)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Dihydrocapsaicin 是一种天然辣椒素,为选择性的TRPV1激动剂,同时可以增加 p-Akt 水平。Dihydrocapsaicin 可以增强低温诱导的神经保护。 |
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Nascimento, P.L.A., Nascimento, T.C.E.S., Ramos, N.S.M., et al.Quantification, antioxidant and antimicrobial activity of phenolics isolated from different extracts of Capsicum frutescens (pimenta malagueta)Molecules19(4),5434-5447(2014)
Choi, C.-H., Jung, Y.-K., and Oh, S.-H.Selective induction of catalase-mediated autophagy by dihydrocapsaicin in lung cell linesFree Radic. Biol. Med.49(2),245-257(2010)
Wu, D., Shi, J., Elmadhoun, O., et al.Dihydrocapsaicin (DHC) enhances the hypothermia-induced neuroprotection following ischemic stroke via PI3K/Akt regulation in ratBrain Res.1671,18-25(2017)
Feketa, V.V., Balasubramanian, A., Flores, C.M., et al.Shivering and tachycardic responses to external cooling in mice are substantially suppressed by TRPV1 activation but not by TRPM8 inhibitionAm. J. Physiol. Regul. Integr. Comp. Physiol.305(9),R1040-R1050(2013)
Sondo, E., Bertelli, R., Pesce, E., et al.High-content screening identifies vanilloids as a novel class of inhibitors of NET formationFront. Immunol.10,963(2019)