Pulegone
Cat. No.：YN360955
| 产品名称: | Pulegone |
| CAS No.: | 89-82-7 |
| Chemical Name: | 5R-methyl-2-(1-methylethylidene)-cyclohexanone |
| Synonyms: | 胡薄荷酮 |
| 分子量: | 152.23 |
| 分子式: | C₁₀H₁₆O |
| SMILES: | O=C1/C(CC[C@@H](C)C1)=C(C)/C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pulegone 是一种具有薄荷-牛至味的芳香草本植物Calamintha nepeta(L.) Savi 的精油的主要化学成分，也是禽类驱虫剂之一。Pulegone 在禽类物种中驱避作用的分子靶点是伤害感受性TRP 锚蛋 1 (TRPA1). Pulegone 刺激鸡感觉神经元中的 TRPM8 和 TRPA1 通道，并在高浓度下抑制前者但不抑制后者。 |
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Choi, Y.Y., Kim, M.H., Lee, H., et al.(R)-(+)-pulegone suppresses allergic and inflammation responses on 2,4-dinitrochlorobenzene-induced atopic dermatitis in mice modelJ. Dermatol. Sci.,(2018)
Cariddi, L., Escobar, F., Moser, M., et al.Monoterpenes isolated from Minthostachys verticillata (Griseb.) Epling essential oil modulates immediate-type hypersensitivity responses in vitro and in vivoPlanta Med.77(15),1687-1694(2011)
