(-)-Menthol
Cat. No.：YN360715
| 产品名称: | (-)-Menthol |
| CAS No.: | 2216-51-5 |
| Chemical Name: | (1R,2S,5R)-5-methyl-2-(1-methylethyl)-cyclohexanol |
| Synonyms: | (-)-薄荷醇 |
| 分子量: | 156.27 |
| 分子式: | C₁₀H₂₀O |
| SMILES: | O[C@H]1[C@H](C(C)C)CC[C@@H](C)C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | (-)-Menthol 是薄荷油的关键成分，(-)-Menthol 结合并激活瞬瞬时受体电位 M8 (TRPM8)，TRPM8 是 Ca2+-可渗透的非选择性阳离子通道，最终增加 [Ca2+]i。 具有抗肿瘤活性。 |
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Kamatou, G.P., Vermaak, I., Viljoen, A.M., et al.Menthol: A simple monoterpene with remarkable biological propertiesPhytochemistry96,15-25(2013)
Miyazawa, M., Watanabe, H., and Kameoka, H.Inhibition of acetylcholinesterase activity by monoterpenoids with a p-menthane skeletonJ. Agric. Food Chem.45(3),677-679(1997)
Lin, J.P., Lu, H.F., Lee, J.H., et al.(-)-Menthol inhibits DNA topoisomerases I, II α and β and promotes NF-Î B expression in human gastric cancer SNU-5 cellsAnticancer Res.25(3B),2069-2074(2005)
Rasoul, M.A.A., Marei, G.I.K., and Abdelgaleil, S.A.M.Evaluation of antibacterial properties and biochemical effects of monoterpenes on plant pathogenic bacteriaAfr. J. Microbiol. Res.6(15),3667-3672(2012)
Galeotti, N., Di Cesare Mannelli, L., Mazzanti, G., et al.Menthol: A natural analgesic compoundNeurosci. Lett.322(3),145-148(2002)
