RN-1747
Cat. No.：YN360700
CAS No. ：1024448-59-6
| 产品名称: | RN-1747 |
| CAS No.: | 1024448-59-6 |
| Chemical Name: | 1-(4-Chloro-2-nitrophenyl)sulfonyl-4-benzylpiperazine |
| Synonyms: | |
| 分子量: | 395.86 |
| 分子式: | C₁₇H₁₈ClN₃O₄S |
| SMILES: | O=S(N1CCN(CC2=CC=CC=C2)CC1)(C3=CC=C(Cl)C=C3[N+]([O-])=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | RN-1747 是选择性的瞬时受体电位阳离子通道 V 型亚家族成员4 (TRPV 4)的激动剂，其对hTRPV4、mTRPV4 和rTRPV4 的EC50值分别为0.77 μM、4.0 μM 和4.1 μM。RN-1747 还能拮抗TRPM8，其IC50值为4.0 μM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Vincent, F.
et al.: Biochem. Biophys. Res. Commun., 389, 490 (2009)
