VU0364770 hydrochloride
Cat. No.：YN320057
CAS No. ：1414842-70-8
规格
价格(RMB)
库存
| 产品名称: | VU0364770 hydrochloride |
| CAS No.: | 1414842-70-8 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 269.13 |
| 分子式: | C₁₂H₁₀Cl₂N₂O |
| SMILES: | O=C(C1=NC=CC=C1)NC2=CC=CC(Cl)=C2.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | VU0364770 hydrochloride 是一种有效的选择性mGlu4正变构调节剂 (PAM)。VU0346770 hydrochloride 对大鼠 mGlu4 和人 mGlu4 受体的EC50分别为 290 nM 和 1.1 μM。VU0364770 hydrochloride 对 mGlu5 具有拮抗活性，EC50为 17.9 μM，VU0364770 hydrochloride 对 mGlu6 具有正变构调节活性，EC50为 6.8 μM。VU0364770 hydrochloride 还对 |
| IC50和靶点: | [{name:"Rat mGlu4:290 nM (EC50)"},{name: "Human mGlu4:1.1 μM (EC50)"},{name: "mGlu6:6.8 μM (EC50)"},{name: "mGlu5:17.9 μM (EC50)"}] |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
