O-Phospho-L-serine
Cat. No.：YN320946
| 产品名称: | O-Phospho-L-serine |
| CAS No.: | 407-41-0 |
| Chemical Name: | O-phosphono-L-serine |
| Synonyms: | L-Serine O-phosphate; L-SOP |
| 分子量: | 185.07 |
| 分子式: | C₃H₈NO₆P |
| SMILES: | OP(OC[C@@H](C(O)=O)N)(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | O-Phospho-L-serine 是 L-serine 合成过程中的直接前体物质，是第三组mGluR(mGluR4，mGluR6，mGluR7 和 mGluR8) 的激动剂，O-Phospho-L-serine 同时为mGluR1和mGluR2的拮抗剂。 |
| IC50和靶点: | |
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Eriksen, L., and Thomsen, C.[3H]-L-2-amino-4-phosphonobutyrate labels a metabotropic glutamate receptor, mGluR4aBr. J. Pharmacol.116(8),3279-3287(1995)
Conn, P.J., and Pin, J.P.Pharmacology and functions of metabotropic glutamate receptorsAnnu. Rev. Pharmacol. Toxicol.37,205-237(1997)
Witting, A., Müller, P., Herrmann, A., et al.Phagocytic clearance of apoptotic neurons by microglia/brain macrophages in vitro: Involvement of lectin-, integrin-, and phosphatidylserine-mediated recognitionJ. Neurochem.75(3),1060-1070(2000)
Bailey, T.J., Fossum, S.L., Fimbel, S.M., et al.The inhibitor of phagocytosis, O-phospho-L-serine, suppresses Müller glia proliferation and cone cell regeneration in the light-damaged zebrafish retinaExp. Eye Res.91(5),601-612(2010)
Saxe, J.P., Wu, H., Kelly, T.K., et al.A phenotypic small molecule screen identifies an orphan ligand-receptor pair that regulates neural stem cell differentiationChem. Biol.14(9),1019-1030(2007)
