VU 0357121
Cat. No.：YN320972
| 产品名称: | VU 0357121 |
| CAS No.: | 433967-28-3 |
| Chemical Name: | 4-butoxy-N-(2,4-difluorophenyl)-benzamide |
| Synonyms: | VU 0357121 |
| 分子量: | 305.32 |
| 分子式: | C₁₇H₁₇F₂NO₂ |
| SMILES: | O=C(NC1=CC=C(F)C=C1F)C2=CC=C(OCCCC)C=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | VU 0357121 是一种高选择性的mGlu5R正变构调节剂 (PAM)，EC50为 33 nM。VU 0357121 对其他 mGlu 受体亚型无活性或具有非常弱的拮抗作用。 |
| IC50和靶点: | [{name:"mGlu5 Receptor:33 nM (EC50)"}] |
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| Solvent & Solubility: |
Hammond, A.X., Rodriguez, A.L., Townsend, S.D., et al.Discovery of a novel chemical class of mGlu5 allosteric ligands with distinct modes of pharmacologyACS Chem. Neurosci.1(10),702-716(2010)
