VU 0364439
Cat. No.：YN320995
CAS No. ：1246086-78-1
规格
价格(RMB)
库存
| 产品名称: | VU 0364439 |
| CAS No.: | 1246086-78-1 |
| Chemical Name: | N-[3-chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-2-pyridinecarboxamide |
| Synonyms: | VU0 364439; VU-0364439 |
| 分子量: | 422.29 |
| 分子式: | C₁₈H₁₃Cl₂N₃O₃S |
| SMILES: | O=C(C1=NC=CC=C1)NC2=CC=C(S(=O)(NC3=CC=CC=C3Cl)=O)C(Cl)=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | VU 0364439是mGlu4阳性变构调节剂（PAM），EC50为19.8 nM。 |
| IC50和靶点: | [{name:"mGlu4 Receptor:19.8 nM (EC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Engers, D.W., Gentry, P.R., Williams, R., et al.Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)Bioorg. Med. Chem. Lett.20(17),5175-5178(2010)
