trans-ACPD
Cat. No.：YN321221
CAS No. ：67684-64-4
| 产品名称: | trans-ACPD |
| CAS No.: | 67684-64-4 |
| Chemical Name: | (1R,3S)-1-aminocyclopentane-1,3-dicarboxylic acid |
| Synonyms: | Trans-(±)-ACP |
| 分子量: | 173.17 |
| 分子式: | C₇H₁₁NO₄ |
| SMILES: | O=C([C@]1(N)C[C@@H](C(O)=O)CC1)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | trans-ACPD 是一种代谢型受体激动剂，促进钙离子活动及产生内向电流。 |
| IC50和靶点: | |
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Kozikowski, A.P., Steensma, D., Araldi, G.L., et al.Synthesis and biology of the conformationally restricted ACPD analogue, 2-aminobicyclo[2.1.1]hexane-2,5-dicarboxylic acid-I, a potent mGluR agonistJ. Med. Chem.41(10),1641-1650(1998)
Pilc, A., Legutko, B., Frankiewicz, T., et al.Trans-(+-)-1-amino-1,3-cyclopentanedicarboxylate (trans-ACPD) stimulates cAMP accumulation in rat cerebral cortical slices but not in glial or neuronal culturesNeurosci. Lett.169(1-2),171-174(1994)
Schoepp, D.D., Johnson, B.G., Salhoff, C.R., et al.In vitro and in vivo pharmacology of trans- and cis-(+-)-1-amino-1,3-cyclopentanedicarboxylic acid: Dissociation of metabotropic and ionotropic excitatory amino acid receptor effectsJ. Neurochem.56(5),1789-1796(1991)
