CTEP
Cat. No.：YN320989
CAS No. ：871362-31-1
| 产品名称: | CTEP |
| CAS No.: | 871362-31-1 |
| Chemical Name: | 2-chloro-4-[2-[2,5-dimethyl-1-[4-(trifluoromethoxy)phenyl]-1H-imidazol-4-yl]ethynyl]-pyridine |
| Synonyms: | RO 4956371; mGluR5 inhibitor |
| 分子量: | 391.77 |
| 分子式: | C₁₉H₁₃ClF₃N₃O |
| SMILES: | FC(F)(F)OC1=CC=C(N2C(C)=C(C#CC3=CC(Cl)=NC=C3)N=C2C)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CTEP (RO 4956371) 是一种新颖的，长效的，可口服的mGlu5 受体别构拮抗剂，IC50值为 2.2 nM，对其选择性是对其他 mGlu 受体的 1000 多倍。 |
| IC50和靶点: | [{name:"mGlu5 Receptor:2.2 nM (IC50)"}] |
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| Solvent & Solubility: |
Lindemann, L., Jaeschke, G., Michalon, A., et al.CTEP: A novel, potent, long-acting, and orally bioavailable metabotropic glutamate receptor 5 inhibitorJ. Pharmacol. Exp. Ther.339(2),474-486(2011)
