CPPHA
Cat. No.：YN320899
CAS No. ：693288-97-0
| 产品名称: | CPPHA |
| CAS No.: | 693288-97-0 |
| Chemical Name: | N-[4-chloro-2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]phenyl]-2-hydroxy-benzamide |
| Synonyms: | N-(4-Chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)phenyl)-2-hydroxybenzamide;CPPHA;N-[4-Chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-2-hydroxybenzamide;N-[4-chloro-2-[(1,3-dioxoisoindol-2-yl)methyl]phenyl]-2-hydroxybenzamide;N-{4-CHLORO- |
| 分子量: | 406.82 |
| 分子式: | C₂₂H₁₅ClN₂O₄ |
| SMILES: | O=C1N(CC2=CC(Cl)=CC=C2NC(C3=CC=CC=C3O)=O)C(C4=CC=CC=C41)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CPPHA 是一种高效、选择性的代谢型谷氨酸受体mGluR5和mGluR1正向变构调制器 (PAM)。CPPHA 可增强 mGluR5 和 mGluR1 对受体激活的反应。CPPHA 被开发用于中枢神经系统疾病的研究。 |
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O'Brien, J.A., Lemaire, W., Wittmann, M., et al.A novel selective allosteric modulator potentiates the activity of native metabotropic glutamate receptor subtype 5 in rat forebrainJ. Pharm. Exp. Ther.309(2),568-577(2004)
