L-APB
Cat. No.：YN320080
| 产品名称: | L-APB |
| CAS No.: | 23052-81-5 |
| Chemical Name: | 2S-amino-4-phosphono-butanoic acid |
| Synonyms: | L-AP 4 |
| 分子量: | 183.10 |
| 分子式: | C₄H₁₀NO₅P |
| SMILES: | O=C(O)[C@@H](N)CCP(O)(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | L-APB 是一种有效的、代谢型谷氨酸受体(mGluR)的特异性激动剂，其对 mGlu4, mGlu8, mGlu6和 mGlu7受体的EC50值分别为 0.13, 0.29, 1.0, 249 μM。 |
| IC50和靶点: | [{name:"mGlu4:0.13 μM (EC50)"},{name: "mGlu8:0.29 μM (EC50)"},{name: "mGlu6:1.0 μM (EC50)"},{name: "mGlu7:249 μM (EC50)"}] |
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Thomsen, C.The L-AP4 receptorGen. Pharmacol.29(2),151-158(1997)
Evans, R.H., Francis, A.A., Jones, A.W., et al.The effects of a series of ω-phosphonic α-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparationsBr. J. Pharmacol.75(1),65-75(1982)
Schoepp, D.D.Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous systemJ. Pharmacol. Exp. Ther.299(1),12-20(2001)
