VU-29
Cat. No.：YN320324
CAS No. ：890764-36-0
| 产品名称: | VU-29 |
| CAS No.: | 890764-36-0 |
| Chemical Name: | |
| Synonyms: | VU 29 |
| 分子量: | 384.39 |
| 分子式: | C₂₂H₁₆N₄O₃ |
| SMILES: | O=C(NC1=CC(C2=CC=CC=C2)=NN1C3=CC=CC=C3)C4=CC=C([N+]([O-])=O)C=C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | VU-29 是代谢型谷氨酸 5(mGlu5)受体的正变构调节剂 (对 rmGluR5 的EC50=9 nM,Ki=244 nM)。相对于其他亚型，VU-29 对 mGluR5 具有选择性 (EC50: rmGluR1/rmGluR2=557 nM/1.5 μM; hmGluR4=154 nM)。 |
| IC50和靶点: | [{name:"rat mGluR5:9 nM (EC50)"},{name: "rat mGluR1:557 nM (EC50)"},{name: "rat mGluR2:1.5 μM (EC50)"},{name: "hmGluR4:154 nM (EC50)"},{name: "rat mGluR5:224 nM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
