DHPG
Cat. No.：YN320621
CAS No. ：146255-66-5
| 产品名称: | DHPG |
| CAS No.: | 146255-66-5 |
| Chemical Name: | α-amino-3,5-dihydroxy-benzeneacetic acid |
| Synonyms: | (RS)-3,5 |
| 分子量: | 183.16 |
| 分子式: | C₈H₉NO₄ |
| SMILES: | O=C(O)C(N)C1=CC(O)=CC(O)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | DHPG ((RS)-3,5-DHPG) 是一种氨基酸，为有效、选择性的第一组代谢型谷氨酸受体mGluR(mGluR 1 和 mGluR 5) 的激动剂，对第二、三组 mGluR 无明显作用。DHPG ((RS)-3,5-DHPG) 也是与磷脂酶 D 耦合的 mGluR 的有效拮抗剂。 |
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Fitzjohn, S.M., Bortolotto, Z.A., Palmer, M.J., et al.The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mGlu receptors in hippocampal synaptic plasticityNeuropharmacology37(12),144-1458(1998)
S.M., C., and García, M.d.C.Activation of spinal metabotropic glutamate receptors elicits cardiovascular responses in pentobarbital anesthetized ratsNaunyn Schmiedebergs Arch Pharmacol.366(4),343-349(2002)
Camón, L., Vives, P., de Vera, N., et al.Seizures and neuronal damage induced in the rat by activation of group I metabotropic glutamate receptors with their selective agonist 3,5-dihydroxyphenylglycineJ. Neurosci. Res.51(3),339-348(1998)
