Fenobam
Cat. No.：YN320149
CAS No. ：57653-26-6
规格
价格(RMB)
库存
| 产品名称: | Fenobam |
| CAS No.: | 57653-26-6 |
| Chemical Name: | N-(3-Chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)urea |
| Synonyms: | 非诺班 |
| 分子量: | 266.68 |
| 分子式: | C₁₁H₁₁ClN₄O₂ |
| SMILES: | O=C(NC1=NC(CN1C)=O)NC2=CC=CC(Cl)=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Fenobam 是一种选择性、口服活性、非竞争性的mGluR5拮抗剂，其作用于变构调节位点 (在大鼠和人重组 mGlu5 受体上的Kd值分别 54 nM 和 31 nM)。Fenobam 具有反向激动剂活性，其阻断 mGlu5 受体活性，IC50为 84 nM。 Fenobam 具有抗焦虑活性。 |
| IC50和靶点: | [{name:"rat mGluR5:54 nM (Kd)"},{name: "human mGluR5:31 nM (Kd)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
